Hefei TNJ chemical industry co.,ltd
Diamond Supplier Enterprise Certification
- Diamond
Supplier - 9th
years
Diamond Supplier Enterprise Certification
Product Certification&
Enterprise Certification
Country: 
China (Mainland)
Business Type:Trading Company
Tel: +86-551-65418695
Tel: 0086-551-65418671
Tel: 0086-551-67199489
Tel: 0551-65418672
Tel: +86 551 6541 8675
Tel: +86-551-65418676
Tel: 0551-65418684
Tel: 0086-551 65418681
Tel: 055165418684
Tel: 0086-551-65418684
Tel: 0086 551-67199490
Mobile: 0086-551-18225849144
Tel: +86-551-65418695
Fax: +86-51-65418697
Province/state: Anhui
City: Hefei
Street: B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China
MaxCard:
Contact Suppliers
CAS NO.142340-99-6
Full experience of large numbers containers loading in main Chinese seaports
Packing with pallet as buyer's special request
Best service after shipment with e-mail
Cargos together with container sales seervice available
Rich experience for exporting
Cargos photo before and after loading into container
Raw materials from chinese origin
Hefei TNJ Chemical Industry Co., limited(ISO 9001: 2008), are strong in the field of Pharmaceuticals,
food additives, plant extract and fine chemicals for more than 10 years.
1.Product description
Product Name: Adefovir dipivoxil
CAS: 142340-99-6
MF: C20H32N5O8P
MW: 501.47
EINECS: 200-001-8
2.Physical properties
Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
3.Specification
|
Test Item |
Analysis Specification |
Result |
|
Description |
crystalline powder |
Conforms |
|
Melting range |
129°C~132°C |
130.8°C-131°C |
|
Loss on drying |
≤0.5% |
0.20 % |
|
Specific rotation |
-58°~-62°(C=1,in CH3OH) |
-61.05° |
|
Sulphated ash |
≤0.1% |
0.08 % |
|
Heavy metals |
≤10ppm |
Conforms |
|
Chlorides |
≤0.02% |
Conforms |
|
Sulfates |
≤0.02% |
Conforms |
|
Fluorine |
14.7%~17.9% |
15.2% |
|
Residual solvent |
Methanol ≤0.2% Isopropanol ≤0.2% Ethyl acetate≤0.2% Chloroform ≤0.2% |
0.0% 0.0% 0.0% 0.0% |
|
Related substances (HPLC) |
Single impurity ≤0.2% Total impurities ≤0.5% |
0.05% 0.08% |
|
Assay |
≥99.5% |
99.92% |
|
Conclusion |
Accordance with the reference
|
|
4.Application
Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. It is approved for the treatment of chronic hepatitis B in adults with evidence of active vir
A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI).
5.Packing
25KG/Drum or as per your requirement