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CAS NO.443-48-1
PProduct information of Metronidazole:
1.Name: Metronidazole
2.Cas No.: 443-48-1
3.MF.: C6H9N3O3
4.Standards: BP
5.Appearance: White or yellowish, crystalline powder
6.Metronidazole is Slightly soluble in water, in acetone, in alcohol and in methylene chloride
7.Mechaninsm of action:Metronidazole, taken up by diffusion, is selectively absorbed by anaerobic bacteria and sensitive protozoas.Metronidazole, taken up by diffusion, is selectively absorbed by and sensitive . Once taken up by anaerobes, it isnon-enzymatically reduced by reacting with reduced , which is generated by pyruvate oxido-reductase. This reduction causes the production of toxic products to anaerobic cells, and allows for selective accumulation in anaerobes.The metronidazole metabolites are taken up into bacterial DNA, and form unstable molecules. This function only occurs when metronidazole is partially reduced, and because this reduction usually happens only in anaerobic cells, it has relatively little effect upon human cells or aerobic bacteria
Specification of Metronidazole
Item Specification
Identification IR
Melting point 159-1630C
Loss on drying 0.5% MAX
Residue on ignition 0.1% MAX
Heavy metals 20ppm MAX
Appearance of solution Suspension II and solution GY6
Impurity 0.1% MAX
Total impurity 0.2% MAX
Disregard limited 0.01% MAX
Specific absorbance 365-395
Assay 99.0-101.0%
Package
1KG, 2KG, 5KG/Aluminium bag with plastic bag inside;
25KG/Drum with plastic bag inside.
According to customers' requirements.