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CAS NO.54-31-9
Appearance A white or almost white crstalline powder
Solubility Practically insoluble in water,soluble in acetone,sparingly soluble in ethanol(96 percent),practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
MP About 210℃, with decomposition
Identification
A Absorption maxima at 228nm,270nm and 333nm
Absorbance ratio A270/A228=0.52 to 0.57.
B The absorption IR of the raw material is accordant to of the standard.
C Should be conform.
Related substances Impurities A,B,C,D,E: for each impurity:NMT0.25%.
Total impurities: NMT0.5%.
Chloride NMT0.02%
Sulfate NMT0.03%
Heavy metals NMT20ppm
Loss on drying NMT0.5%
Sulphated ash NMT0.1%
Residual solvents Should be conform
Assay 98.5%~101.0%(dried substance)
Product Information
Chemical Name Furosemide
CAS # 54-31-9
Formula C12H11ClN2O5S
Molecular Weight 330.74
Synonyms Furosemide; Furosemid; 2-furfurylamino-4-chloro-5-sulfamoylbenzoic acid;
Physical Properties
Melting point: 220 °C (dec.)(lit.)
Density: 1.606
Flash point: 11°C
Furosemide is a white or off-white crystalline powder, odorless, almost tasteless. It is dissolved in acetone, slightly soluble in ethanol, but insoluble in water.
Specification:
Appearance A white or almost white crstalline powder
Solubility Practically insoluble in water,soluble in acetone,sparingly soluble in ethanol(96 percent),practically insoluble in methylene chloride. It dissolves in dilute solutions of alkali hydroxides.
MP About 210℃, with decomposition
Identification
A Absorption maxima at 228nm,270nm and 333nm
Absorbance ratio A270/A228=0.52 to 0.57.
B The absorption IR of the raw material is accordant to of the standard.
C Should be conform.
Related substances Impurities A,B,C,D,E: for each impurity:NMT0.25%.
Total impurities: NMT0.5%.
Chloride NMT0.02%
Sulfate NMT0.03%
Heavy metals NMT20ppm
Loss on drying NMT0.5%
Sulphated ash NMT0.1%
Residual solvents Should be conform
Assay 98.5%~101.0%(dried substance)