Hefei TNJ chemical industry co.,ltd
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POWDER DOXYCYCLINE HCl
CAS NO.: 10592-13-9
Molecular Weight: 480.90
Molecular Formula: C22H25ClN2O8
Standard: USP/BP/EP
Usage: pharmaceutical intermediates
Specifications of Doxycycline Hyclate BP2007:
|
Items |
Specifications |
Results |
|
Appearance |
Yellow crystalline powder |
Complies |
|
PH Value |
2.0 ~ 3.0 |
2.4 |
|
Specific optical rotation |
-105°~-120° |
-110° |
|
Specific absorbance |
At 349nm: 300 ~ 335 |
317 |
|
Light absorbing impurities |
At 490nm ≤0.07 |
0.03 |
|
Related substances |
6-Epidoxycycline ≤2.0% |
Complies |
|
Methacycline ≤2.0% |
Complies |
|
|
Disregard limit ≤0.1% |
Complies |
|
|
Any individual impurity ≤0.5% |
Complies |
|
|
Ethanol |
4.3% ~ 6.0%(m/m) |
4.8% |
|
Heavy metals |
≤50ppm |
Complies |
|
Water |
1.4% ~ 2.8% |
2.0% |
|
Sulphated ash |
≤0.4% |
0.08% |
|
Assay |
95.0% ~ 102.0% of C22H25CIN2O8 (anhydrous,ethanol-free substance) |
98.3% |
POWDER DOXYCYCLINE HCl
CAS NO.: 10592-13-9
Molecular Weight: 480.90
Molecular Formula: C22H25ClN2O8
Standard: USP/BP/EP
Usage: pharmaceutical intermediates
Specifications of Doxycycline Hyclate BP2007:
|
Items |
Specifications |
Results |
|
Appearance |
Yellow crystalline powder |
Complies |
|
PH Value |
2.0 ~ 3.0 |
2.4 |
|
Specific optical rotation |
-105°~-120° |
-110° |
|
Specific absorbance |
At 349nm: 300 ~ 335 |
317 |
|
Light absorbing impurities |
At 490nm ≤0.07 |
0.03 |
|
Related substances |
6-Epidoxycycline ≤2.0% |
Complies |
|
Methacycline ≤2.0% |
Complies |
|
|
Disregard limit ≤0.1% |
Complies |
|
|
Any individual impurity ≤0.5% |
Complies |
|
|
Ethanol |
4.3% ~ 6.0%(m/m) |
4.8% |
|
Heavy metals |
≤50ppm |
Complies |
|
Water |
1.4% ~ 2.8% |
2.0% |
|
Sulphated ash |
≤0.4% |
0.08% |
|
Assay |
95.0% ~ 102.0% of C22H25CIN2O8 (anhydrous,ethanol-free substance) |
98.3% |