Product Certification&
Enterprise Certification
Country: China (Mainland)
Business Type:Trading Company
Tel: +86-551-65418695
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Tel: 0086-551-67199489
Tel: 0551-65418672
Tel: +86 551 6541 8675
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Mobile: 0086-551-18225849144
Tel: +86-551-65418695
Fax: +86-51-65418697
Province/state: Anhui
City: Hefei
Street: B911 Xincheng Business Center, Qianshan Road, Hefei Anhui China
MaxCard:
CAS NO.124750-99-8
Our Advantages:
GMP factory
Full experience of large numbers containers loading in main Chinese seaports
Packing with pallet as buyer's special request
Best service after shipment with e-mail
Cargos together with container sales seervice available
Rich experience for exporting
Cargos photo before and after loading into container
Raw materials from chinese origin
Hefei TNJ Chemical Industry Co., limited(ISO 9001: 2008), are strong in the field of Pharmaceuticals,
food additives, plant extract and fine chemicals for more than 10 years.
Service we can provide:
1). Mixed container: We can mix different items in one container.
2). Quality control: Before shipment, we can provide free sample for test. Inspection before shipping.
3). Packing: We can pack according to your requirements and also give you some other packing methods for reference and suggest adequate packing methods according to global trend. We will send you photo of goods before shipment.
4). Prompt shipment: We usually can ship the goods within 7 days for 1*20'FCL conatiner after order confirmed and also provide professional shipping documents for your Customs clearance.
5). We work closely with DHL, FEDEX, UPS,ETC., we can ship samples and small quantity goods to you fast and safe.
We work closely with famous airline companies like BA,PO,OZ,CX,UPS,LA,TG,TA,ET,etc. and professional vessel companies like MSK,"K"LINE,CMA,CSAV,ZIM,WANHAI,HAMBURG-SUD,etc. We can ship bulk quantity to you quick and safe.
6). We can provide door to door shipment in many countries.
1.Product description
Product Name: Losartan potassium
CAS: 124750-99-8
MF: C22H23ClKN6O
MW: 462.01
2.Physical properties
Appearance:white crystaliinr powder
Solubility:
Freely soluble in water, soluble in Isopropyl
Alcohol, slightly soluble in Acetonitrile
3.Specification
Item |
Standards |
Results |
Characters |
White or almost white crystalline powder |
White crystalline powder |
Identification |
Infrared absorption: Must similar to reference standard |
Conforms |
Ultraviolet absorption: Must similar to reference standard |
Conforms |
|
Test for potassium: Must be positive |
Positive |
|
Water |
NMT 0.5% |
0.1% |
Heavy metals |
NMT 0.001% |
Conforms |
Chromatographic purity |
Any individual impurity NMT 0.2% |
0.01% |
Total impurities NMT 0.5% |
0.04% |
|
Residual solvents |
Cyclohexane NMT 0.1% |
0.007% |
Isopropyl alcohol NMT 0.2% |
0.03% |
|
Assay(HPLC) |
98.5~101.0% |
99.2% |
4.Application
Losartan is a selective, competitive angiotensin II receptor type 1 (AT1) receptor antagonist, reducing the end
organ responses to angiotensin II. Losartan administration results in a decrease in total peripheral resistance
(afterload) and cardiac venous return (preload) All of the physiological effects of angiotensin II, including stimulation
of release of aldosterone, are antagonized in the presence of losartan. Reduction in blood pressure occurs independently
of the status of the renin angiotensin system. As a result of losartan dosing, plasma renin activity increases due to removal of the angiotensin II feedback.
Losartan is a uricosuric. Because losartan can cause hyperkalemia, potassium supplements or salt substitutes containing potassium
should not be used without appropriate monitoring by a physician.
5.Packing
25KG/Drum or as per your requirement