Hefei TNJ chemical industry co.,ltd
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Supplier - 10th
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Diamond Supplier Enterprise Certification
Product Certification&
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China (Mainland)
Business Type:Trading Company
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CAS NO.142340-99-6
Full experience of large numbers containers loading in main Chinese seaports
Packing with pallet as buyer's special request
Best service after shipment with e-mail
Cargos together with container sales seervice available
Rich experience for exporting
Cargos photo before and after loading into container
Raw materials from chinese origin
Hefei TNJ Chemical Industry Co., limited(ISO 9001: 2008), are strong in the field of Pharmaceuticals,
food additives, plant extract and fine chemicals for more than 10 years.
1.Product description
Product Name: Adefovir dipivoxil
CAS: 142340-99-6
MF: C20H32N5O8P
MW: 501.47
EINECS: 200-001-8
2.Physical properties
Adefovir dipivoxil is a white to off-white crystalline powder with an aqueous solubility of 19 mg/mL at pH 2.0 and 0.4 mg/mL at pH 7.2. It has an octanol/aqueous phosphate buffer (pH 7) partition coefficient (log p) of 1.91.
3.Specification
|
Test Item |
Analysis Specification |
Result |
|
Description |
crystalline powder |
Conforms |
|
Melting range |
129°C~132°C |
130.8°C-131°C |
|
Loss on drying |
≤0.5% |
0.20 % |
|
Specific rotation |
-58°~-62°(C=1,in CH3OH) |
-61.05° |
|
Sulphated ash |
≤0.1% |
0.08 % |
|
Heavy metals |
≤10ppm |
Conforms |
|
Chlorides |
≤0.02% |
Conforms |
|
Sulfates |
≤0.02% |
Conforms |
|
Fluorine |
14.7%~17.9% |
15.2% |
|
Residual solvent |
Methanol ≤0.2% Isopropanol ≤0.2% Ethyl acetate≤0.2% Chloroform ≤0.2% |
0.0% 0.0% 0.0% 0.0% |
|
Related substances (HPLC) |
Single impurity ≤0.2% Total impurities ≤0.5% |
0.05% 0.08% |
|
Assay |
≥99.5% |
99.92% |
|
Conclusion |
Accordance with the reference
|
|
4.Application
Adefovir Dipivoxil(Preveon, Hepsera) works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. It is approved for the treatment of chronic hepatitis B in adults with evidence of active vir
A nucleotide analog, useful as an oral reverse transcriptase inhibitor (ntRTI).
5.Packing
25KG/Drum or as per your requirement