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Hefei TNJ chemical industry co.,ltd

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Amiodarone hydrochloride

CAS NO.19774-82-4

  • Min.Order: 1 Kilogram
  • Payment Terms: L/C,T/T,Other
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Product Details

Keywords

  • Amiodarone hydrochloride
  • Amiodarone hydrochloride
  • 19774-82-4

Quick Details

  • ProName: Amiodarone hydrochloride
  • CasNo: 19774-82-4
  • Molecular Formula: C25H29I2NO3.ClH
  • Appearance: White Solid
  • Application: Antiarrhythmic;Na+ channel blocker
  • DeliveryTime: 3-5 days
  • PackAge: 25kg/drum or acc to customers' request
  • Port: Shanghai Port
  • ProductionCapacity: 100 Metric Ton/Week
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: acc to customers' request
  • LimitNum: 1 Kilogram

Superiority

APIs

Details

Product name: Amiodarone Hcl

CAS NO: 19774-82-4

EINECS No.: 243-293-2

MW: 681.77

Appearance: white crystalline powder

Melting Range: 159~163°C

Purity:99%

Specification 

Items

Specifications

Results

Characters

 

 

Appearance

White   or almost white, fine crystalline powder

conforms

Solubility

Very   slightly soluble in water, freely soluble in methylene chloride, soluble   methanol, sparingly soluble in ethanol(96%)

conforms

Identification

 

 

A)   IR

Conforms   to Amiodarone HCL CRS

Conforms

B)   Chlorides

It   gives reactions of chlorides

Conforms

Appearance   of solution

clear,   NMT GY5

Conforms

Melting   Range

159~163°C

159.0~160.0°C

pH

3.2~3.8

3.63

Impurity   H (by TLC)

NMT   0.02%

<0.02%

Related   Substance (by HPLC 

 

 

Impurity   A

NMT   0.20%

0.07%

Impurity   B

NMT   0.20%

0.10%

Impurity   C

NMT   0.20%

conforms

Impurity   D

NMT   0.20%

0.05%

Impurity   E

NMT   0.20%

0.03%

Impurity   F

NMT   0.20%

conforms

Impurity   G

NMT   0.20%

0.01%

Unspecified   impurities

NMT   0.20%

0.02%

Total   impurities

NMT   0.20%

0.34%

Iodides

NMT   150ppm

<150ppm

Heavy   metals

NMT   20ppm

<20ppm

Loss   on drying

NMT   0.5%

0.08%

Sulphated   ash

NMT   0.1%

0.02%

Assay

98.5%~101.0%

100.00%

Residual   Solvents

 

 

Ethanol

NMT5000ppm

782ppm

Toluene

NMT890ppm

94ppm

Conclusion

The   results can conforms with the EP6

 Usage

1) Amiodarone Hcl is an anti-arrhythmic agent used for various types of cardiac dysrhythmias, both ventrucular and artrial.

2) It is also used in arrhythmias that are otherwise difficult to treat with medication.

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