Keywords

• 70288-86-7
• Ivermectin
• mk-093

Quick Details

• ProName: GMP Ivermectin
• CasNo: 70288-86-7
• Molecular Formula: C48H74O14
• Appearance: white powder
• Application: medical or veterinary use
• DeliveryTime: within one week after payemnt confirme...
• PackAge: 25kg/drum 20kg/drum 1kg/tin 5kg/tin
• Port: China main ports
• ProductionCapacity: 1000 Metric Ton/Year
• Purity: 99.9%
• Storage: stored in cool and dry place
• Transportation: by sea, by express ,by air
• LimitNum: 1 Kilogram
• Heavy Metal: 10ppm max
• Valid Period: 2 years when properly stored

Superiority

Ivermectin is widely used in cattle, sheep, horses, pigs, gastrointestinal nematodes, lung nematodes and parasitic arthropod, canine intestinal nematodes, ear mites, scabies mites, silk worm and microfilariae, gastrointestinal nematodes and external parasites and poultry. This product belong to the broad-spectrum drug resistant parasites.

Ivermectin for a variety of most of the life cycle of nematodes (but not all nematodes) role; For dish tail filarial microfilariae effectively, but for adult worms; For only in intestinal fecal round worms are also effective.

Ivermectin has the selective inhibitory effect, with no spinal nerve cells and muscle cells in the animal glutamic acid chlorine ion channels of the valve is the high binding affinity, leading to the proliferation of the chloride ion permeability of cell membrane, cause nerve cells or muscle cells hyperpolarization, parasites paralysis or death.

Details

Name: Ivermectin 

CAS No: 70288-86-7

EINECS No: 274-536-0

Molecular Formular: C95H146O28

Molecular Weight: 1736.16

Appearance: White crystalline powder

Solubility: soluble in acetone, very slightly soluble in hot water and n-octanol, insoluble in cold water and methanol.

[Medical Uses]

Ivermectin is a broad-spectrum antiparasitic agent, traditionally against parasitic worms. It is mainly used in humans in the treatment of onchocerciasis (river blindness), but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis, filariasis and enterobiasis), and some epidermal parasitic skin diseases, including scabies.

[Veterinary Uses]

In veterinary medicine ivermectin is used against many intestinal worms (but not tapeworms), most mites, and some lice. Despite this, it is not effective for eliminating ticks, flies, flukes, or fleas. It is effective against larval heartworms, but not against adult heartworms, though it may shorten their lives. The dose of the medicine must be very accurately measured as it is very toxic in over-dosage.

It is sometimes administered in combination with other medications to treat a broad spectrum of animal parasites. Some dog breeds (especially the Rough Collie, the Smooth Collie, the Shetland Sheepdog, and the Australian Shepherd), though, have a high incidence of a certain mutation within the MDR1 gene (coding for P-glycoprotein); affected animals are particularly sensitive to the toxic effects of ivermectin. 

Clinical evidence suggests kittens are susceptible to ivermectin toxicity. A 0.01% ivermectin topical preparation for treating ear mites in cats (Acarexx) is available.

Ivermectin is sometimes used as an acaricide in reptiles, both by injection and as a diluted spray. While this works well in some cases, care must be taken, as several species of reptiles are very sensitive to ivermectin. Use in turtles is particularly contraindicated.